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New Study Finds THC Kills Prostate Cancer Cells

Recent studies show that THC may play a powerful role in how we treat prostate cancer in the future. If you are asking yourself, “What can’t cannabis do?” Well, the results are in and THC kills cancer cells by inducing apoptosis in diseased cells.

Disclaimer: if you are battling cancer, this is not your cue to drop your current treatment in place of cannabis. Talk to your medical provider or find an ND that can help you tailor your treatment to include cannabis.

THC and How it Affects the Body

THC is the most commonly known cannabinoid found in marijuana and provides the mind and body with a broad spectrum of psychoactive and immuno-active effects.

 

Common effects of THC

Prostate Cancer - effects of THC

 

 

 

 

 

 

 

 

 

 

 

 

Some are fun, some make you unproductive, and other times they are lifesavers. Here is a short list of commonly reported effects of THC:

  • Coordination and movement altered
  • Short-term memory
  • Canna-giggles
  • Stabilizes mood and emotion
  • Balance in biochemistry
  • Sleep aid
  • Aphrodisiac

 

The Endocannabinoid System

THC works in the body by binding to receptors found in the endocannabinoid system. Many of these receptors are found in the brain and in the tissues outside the central nervous system. So far there have been two receptors that have been identified:

  • CB1 – modulates the brain and the reproductive organs
  • CB2 – affects immune tissues

Many ailments have been attributed to an endocannabinoid deficiency and supplementation of the system through cannabinoids from marijuana has been found to be an effective treatment of those ailments.

Cancer and THC

In recent studies, cannabinoids – THC & CBD – have been shown to induce apoptosis, or cell suicide, in diseased cells. More notably, causing cell death in cancer cells.

 

How We Know a Cell is Dying

 

cell death in prostate cancer

 

The biochemical signals that indicate cell death are not well known, but some consider ceramide as an important regulator of cell death.

  • Reduction in size of cell
  • Condensed chromatin (molecule that packs your DNA in the nucleus)
  • Redistribution of plasma
  • Changes in the surface of the cell
Prostate Cancer & Treatment with THC

Why does THC help fight prostate cancer, specifically? Although, cannabinoids are mainly produced or received in the brain, recent findings show that they are also produced in the testis. (remember, CB1 receptors modulate the brain and reproductive organ function.)

This finding led researchers to test how powerful of an ally THC can be in the fight against prostate cancer. They studied PC-3 (prostate cancer cells), their growth factors and how they react to THC in comparison to ceramide, a commonly attributed trigger to cell death.

The study tested different doses of THC on prostate cancer cells to see if there was a link between cell death in prostate cancer cells treated with THC. Researchers found THC caused a dramatic drop in the viability of the cells and cell death occurred after 2-3 days. The peak effect was observed at day 6 of treatment with the dosed THC.

Furthermore, the study found that the cell death induced by THC happened as a receptor-independent mechanism. So cannabinoids are now known to regulate cell death and growth independent of any other function in the body – not disrupting the normal function or mechanism of your biochemistry.

Cannabis Infused Drinks: How Do They Work?

Cannabis Infused Drinks: How Do They Work?

Cannabis infused drinks date back to 1000 BC with a drink known as Bhang, infused with cannabis and  combined with milk. Bhang was used as an anesthetic and to treat a variety of human illnesses. Cannabis drinks have since grown in popularity over the years, and can often be more effective than edible cannabis products. Bioactive compounds like terpenoids, flavonoids, and cannabinoids make cannabis beverages extremely bioavailable, ranging from 50-75%. Bioavailability is the amount of a substance that enters circulation when introduced to the body, allowing it to make cognitive or physiological changes. The high bioavailability of cannabis infused drinks means that its effects are more consistent than other methods of cannabis consumption- like eating edibles and smoking. Edibles have a much lower bioavailability at 10-20% because of their journey through the body. Edibles are processed through the gastrointestinal tract where THC is absorbed into the bloodstream and passes through the liver. Liver enzymes hydroxylate THC, forming 11-OH-THC, a psychoactive metabolite that can cross the blood-brain barrier. Not all of the substance transmits to the brain every time. This complex process and inconsistent dosage can result in symptoms of anxiety and overall unpredictable effects. Smoking cannabis can be 2-56% bioavailable, based on dependent variables- like smoking mechanics and duration.

Bioactive Compounds:

Flavonoids: aromatic molecules that contribute to the taste and smell of plants- flavonoids enhance the natural flavors present in cannabis infused drinks like CannaBucha.

Terpenoids: Terpenoid compounds or terpenes are essential oil components found in nature, and form

the largest group of chemical constituents found in plants. Terpenoids can affect mood, memory, stress, and the ability to concentrate.

Cannabinoids: Cannabinoids are the chemical compounds that communicate with receptors that make us feel the effects of cannabis. Most receptors are located in the brain which is why cognitive changes occur when consuming cannabis products.

 

Health Benefits

Cannabis infused drinks are often times a much healthier option than other cannabis products available on the market. Many edible products are associated with more indulgent foods that use carbohydrates, sugars, and fats as carriers for cannabinoids. Cannabis infused beverages like Kombucha and Coffee are a much better option for health-conscious cannabis consumers.

 

Cannabis Infused Drinks

As cannabis infused drinks have become increasingly popular, there are more options on the market combining your favorite drinks with cannabis!       

 

Kombucha + Cannabis = CannaBucha

 

Kombucha has been around for over 2000 years and is referenced in Ancient Chinese culture as the “immortal elixir.” Kombucha is a fermented tea drink that is rich in probiotics that aid digestion, promotes gut health, and prevents cancer. It also has positive psychoactive effects- including mood stabilization, mental clarity, and improved concentration.

CannaBucha combines the bioavailable compounds extracted from trichromes and combines them with the popular GTs Kombucha recipe, creating undeniably delicious flavor- available in three varieties. Together, Kombucha and Cannabis encourage an uplifting, mellow high that sets about 15 minutes after your first sips. CannaBucha is a great way to bring clarity throughout your day, and make your body feel great too! Available in “The Grapes,” “Strawberry Forever,” and “Homemade Lemonade” these refreshing drinks will surely quench your thirst!

Coffee + Tea + Cannabis = Therapy Tonics

 

For you coffee and tea lovers out there, Therapy Tonics takes some of our favorite drinks and makes them better! Available in Vanilla Caramel, Indian Spice Chai, Coconut Matcha, and Mexican Mocha, these drinks are infused with high-quality sativa strains for a mellow, uplifting high. We love Vanilla Caramel Coffee to get our day going- it’s a focused, uplifting, and productive high. Indian Spiced Chai is a clear and enlightening drink with warm, spiced flavors, originating from a traditional Indian Spiced Chai recipe. Coconut Matcha is a vegan drink using coconut milk that makes for a smooth, energetic feeling. Who doesn’t love Mexican Mocha? The rich chocolate with a hint of spice- we love the vitalizing effects and delicious flavor of this Therapy Tonics drink.

Research Finds – 4 Ways Cannabis Kills Cancer Cells

Cannabis Kills Cancer Cells

Turns out cannabis is not only useful in mitigating the symptoms of chemotherapy, as it has been used to treat in the past, but cannabis kills cancer cells. How do we know? Studies and advancement in research on the effects cannabis has on cancer treatment has exploded in recent years. Because of the increased interest on cannabis as a cancer treatment, researchers have found that cannabis helps to kill cancer cells while remaining non-invasive and healing making it an ideal complement to chemotherapy and radiation treatment.

It is important to note that cannabis is NOT considered a cure for cancer and not all cancers respond to cannabis and the cannabinoids it supplies to your body – course of action in terms of treatment should always be discussed with your medical professional.
 

4 Ways Cannabis Kills Cancer

 
Recent studies and preclinical evidence has led researchers to believe that there are four main ways that cannabis works to halt cancer growth and kill cancer cells when used as a supplementary treatment to conventional methods.
 

  1. Halted Proliferation
  2. Cancer cells proliferate when they divide and make new cancer cells causing tumors to grow; THC & CBD have been seen to stop cancer cell growth in ten types of cancer including:

    • Melanoma
    • Prostate
    • Breast
    • Lung
    • Colon

     

  3. Death by Starvation
  4. Tumors cannot grow if they cannot eat; cannabis is anti-angiogenic meaning it turns off the genes that allow tumors to develop blood vessels. No blood, no oxygen, no nutrients, no growth.
     

  5. Decreased Spread
  6. THC & CBD prevents metastasis in lab and rodent models leading to hope that it can help to prevent the spread of cancer to other parts of the body in cancer patients.
     

  7. Triggered Cell Death
  8. Cannabis kills cancer cells because THC & CBD tap into the body’s natural mechanism that decides if diseased cells will live or die. Deciding the latter means that the cell will undergo one of the following:

    • Triggers Apoptosis – cell suicide
    • Triggers Autophagy – autodigestion of cell

 
Research continues on cancer treatment and how cannabis kills cancer cells and it is important to understand that new findings are in preclinical settings and are in the early phases. However, the recent findings have shown a positive correlation between cannabis and cancer treatment giving hope to the medical community and cancer patients alike. Always talk to your doctor before incorporating cannabis into your cancer treatment plan. Find cannabis savvy medical resources to help guide you in deciding if cannabis is the right course of action for you.

Breast Cancer and CBD: Cure on the Horizon?

Breast Cancer and CBD

A recent study by the Ohio State University Medical Center has shown promise and positive correlation between the treatment of breast cancer with the use of cannabis, specifically with doses of the non-psychoactive cannabinoid, CBD.
 

Cancer Cell Characterization: What We Know About Breast Cancer

 
Cell proliferation is one of the most important characterizations of cancer cells, how they survive and how tumor masses form. When there is a high concentration of stimuli from epidermal growth factor (EGF), cells will reconstruct themselves to become more sticky allowing them to migrate around the body. The signaling by EGF/EGFR in TNBC cells are important in creating the pathways that contribute to cancer cell survival, migration, cell growth and metastasis.

Breast cancer survival is limited in part because of metastasis and distant migration of cancer cells. Breast cancer cells exhibit high levels of NF-kB activation and overexpression of EGFR, the crucial component for cell growth and metastasis.
 

How CBD Helps Breast Cancer Patients

 
The study found that CBD significantly inhibited the proliferation of cancer cells induced by EGF. This means that CBD has the ability to inhibit tumor growth, metastasis, and modulate cancer microenvironment; all good news for advancement in treating aggressive, drug resistant breast cancer cells.
 

Treating Breast Cancer with CBD

 
It is important to note that chemotherapy is still the first line of defense in many cancer treatments. Cancer treatments vary by diagnosis and prognosis and should always be discussed with your oncologist.
 
Breast Cancer & CBD Treatment

 
Cannabinoids have been used for many years in cancer therapy. This is due, in large part, to its abilities to mitigate symptoms of conventional cancer therapy and treatment and its recent development as a potent complement to such treatments. Furthermore, the recent study on CBD and its ability to inhibit cancer cell growth and migration in TNBC breast cancer cells suggests that the cannabinoid has the potential to be used as an anti-tumor drug while remaining anti-invasive.
 

Apoptosis – Cell Death

The recent study out of the Ohio State University Medical Center has provided evidence that cannabinoids, such as CBD, can trigger apoptosis. What does this mean? Apoptosis is essentially cell suicide. Your body already has this mechanism in place, but cancer overpowers the system and does not allow your body to effectively fight back. Cannabinoids trigger your body’s mechanism to target the bad cells and cell death of these diseased cells follows.

 

Chemotherapy Symptom Mitigation
  • Modulate pain
  • Anti-inflammatory properties
  • Cell growth inhibition
  • Apoptotic effects

 

What Does This Mean for Cancer Patients?

 
Cannabis helps reduce painful symptoms associated with conventional cancer treatment while supplementing the body’s healing process. Because bad cells along with good cells are attacked during chemotherapy the most powerful source of healing is through sleep. Cannabis aids in sleep and restoration of good cells while inhibiting the growth of bad cells.

As stated before, always consult your healthcare provider before changing the course of any medical treatment. All treatments are unique to individuals as well as reactions and tolerance to cannabis.

Migraines: Does Cannabis Help Reduce the Symptoms?

CANNABIS AND MIGRAINES

Cannabis has been used for its medicinal properties for centuries. Treating headaches and migraines with cannabis? Some evidence points to cannabis being the lead prescription in the 6th and 7th centuries to help patients find relief from headache symptoms. What does it do for a migraine?

Where Do Migraines Come From?

Emerging research suggests that migraines are linked to clinical endocannabinoid deficiency (CECD) in patients. Endocannabinoids are the body’s natural cannabis. A decrease in certain endocannabinoids can lead to some of the symptoms associated with a migraine.

How Does Cannabis Help?

Migraines are often associated with lower levels of the “bliss hormone” within the endocannabinoid system. Cannabis works to relieve some of the symptoms of a migraine by supplementing or restores cannabinoid levels to the endocannabinoid system causing you to feel relief from migraine symptoms. Although it doesn’t fully cure the symptoms it greatly reduces them to the point that patients experience a reduction in the intensity or sometimes the frequency of the migraine symptoms.

Want to know more? CLICK HERE to read more.

5 Ways Cannabis Reduces Migraine Symptoms
  1. fights inflammation
  2. eases pain
  3. fights nausea
  4. lifts mood
  5. aids in sleep

 
Cannabis and Migraines